Intraneuronal accumulation of abnormal phosphorylated tau (p-tau) is a molecular pathology in many neurodegenerative tau......

Introduction: Trolox with potent antioxidant properties, would be against the responses of the ubiquitin proteasome path......

All-trans retinoic acid (ATRA) has been successfully used in differentiation therapy for acute promyelocytic leukemia (A......

目的:探讨抗氧化剂Trolox对运动后大鼠骨骼肌泛素蛋白酶体途径降解蛋白质的影响.方法:42只雄性SD大鼠随机分为2组,对照组24只(运动......

泛素蛋白酶体途径是真核生物体内最重要的蛋白质降解途径之一，其中，目标蛋白的泛素化过程涉及泛素激活酶、泛素结合酶和泛素蛋白连接......

目的:采用球囊拉伤新西兰白兔颈总动脉,复制出血管损伤后狭窄模型;在损伤血管局部应用蛋白酶体抑制剂MG132,观察蛋白酶体抑制剂MG1......